请使用支持JavaScript的浏览器!
主营:分子类,蛋白类,抗体类,生化类试剂
banner
当前位置: 首页 > 产品中心 > Product Family > affinity biologicals/Factor VII Polyclonal Antibody - Affinity Purified - FITC Conjugated/0.1mg vial/SAFVII-APFTC
问答列表

    暂无问答

affinity biologicals/Factor VII Polyclonal Antibody - Affinity Purified - FITC Conjugated/0.1mg vial/SAFVII-APFTC

  • 产品编号: SAFVII-APFTC
  • 美  元  价: 待定
  • 市  场  价: ¥0.00
  • 品       牌:
  • 产       地: 美国(厂家直采)
  • 公       司: affinitybiologicals
  • 产品分类:
  • 公司分类: Product Family
affinity biologicals/Factor VII Polyclonal Antibody - Affinity Purified - FITC Conjugated/0.1mg vial/SAFVII-APFTC
  • affinity biologicals/Factor VII Polyclonal Antibody - Affinity Purified - FITC Conjugated/0.1mg vial/SAFVII-APFTC
商品介绍

Description

Factor VII Polyclonal Antibody – Affinity Purified – FITC Conjugated

Affinity’s Factor VII Polyclonal Antibody – Affinity Purified – FITC Conjugated is the highest level of our Fluorescein Isothiocyanate (FITC) Factor VII antibodies.  During the Antigen Affinity Purification process the IgG has had any non-specific immunoglobulin fraction eliminated which enriches the specificity of the remaining immunoglobulin towards the target antigen.  The result is a very high-purity product with a substantially higher titre than whole or purified IgG.  Our Factor VII Polyclonal Antibody – Affinity Purified – FITC Conjugated is provided in a solution of HEPES buffered saline containing 50% glycerol (v/v) and has been conjugated with FITC as an enzyme reporter.  This antibody is generally intended for use as labelled primary antibodies in applications such as immunoassay and immunoblotting.


Product Code: SAFVII-APFTC

Retail Product Size: 0.1mg vial

Host Animal: Sheep Anti-Human Factor VII Polyclonal Antibody – Affinity Purified – FITC Conjugated

Species Cross Reactivity: View Chart

Product Datasheet: Factor VII F7 Polyclonal Antibody - FITC conjugated anti-human sheep IgG


Description of Factor VII

Factor VII (FVII, also known as Stable Factor and Proconvertin) is a vitamin K-dependent glycoprotein produced in the liver. Plasma concentration of FVII is normally ~0.5 μg/ml (10 nM) in plasma. A deficiency of FVII is associated with bleeding in a clinical pattern similar to haemophilia, but is inherited as an autosomal recessive trait. The deficiency can be characterized by a quantitative (low activity and low antigen) or a qualitative (low activity and normal antigen) defect in FVII function. In its zymogen form FVII is a single chain molecule of ~50 kDa. It contains two EGF-like domains and an amino-terminal domain containing 10 γ-carboxyglutamic acid (Gla) residues. These Gla residues allow FVII to bind divalent metal ions and participate in calcium-dependent binding interactions. FVII and activated FVII (FVIIa) bind to tissue factor exposed at the site of vascular injury. FIXa, FXa or FVIIa rapidly activate tissue factor-bound FVII to FVIIa in the presence of calcium and phospholipid. Thrombin and FXIIa are able to activate FVII in the fluid phase in the absence of cofactors. The activation of the single chain zymogen FVII occurs by proteolysis after residue Arg152, resulting in a two-chain active serine protease consisting of a 30 kDa heavy chain and a 18 kDa light chain. In complex with tissue factor, phospholipid and calcium, FVIIa is able to activate F.X and F.IX. Free FVIIa in plasma is remarkably stable, but the activity of FVIIa/TF complex is regulated by Tissue Factor Pathway Inhibitor (TFPI) in the presence of F.Xa, and also by Antithrombin (ATIII) in the presence of heparin1-3.

References and Reviews

1. Rao LVM, Bajaj SP, Rapaport SI; Activation of Human Factor VII During Clotting in Vitro; Blood 65, pp 218-226, 1985.

2. Lawson, JH, Butenas S, Ribarik N, Mann KG; Complex-dependent Inhibition of Factor VIIa by Antithrombin III and Heparin; JBC 268 pp 767-770, 1993.

3. Nemerson Y, in Hemostasis and Thrombosis, 3rd Edition, eds. RW Colman, J Hirsh, VJ Marder and EW Salzman, pp. 81-93, J.B. Lippincott Co., Philadelphia PA, USA, 1994.

品牌介绍

Affinity Biologicals,Inc.是全球范围内用于血栓形成和止血研究与诊断的产品的主要制造商。我们的产品包括广泛的抗体,结合物,用于人类和动物分析物免疫测定的抗体对,完整的ELISA试剂盒的VisuLize系列以及包括VisuDep免疫缺陷因子缺乏血浆,VisuCal校准血浆的全系列人类血浆产品和VisuCon控制血浆。服务包括蛋白质纯化,抗体生产,测定开发,定制制造(包括定制冻干和能力验证材料)。


蚂蚁淘(ebiomall)作为一家生命科学领域的垂直电商平台,公司专注生物医学科研用品的全球导购和品牌推广,为海内外厂方与代理经销商搭建跨境贸易系统和交流平台。产品齐全,200+分类,1000+品牌,500万+产品信息。100%正品,专业售后,到货快,在线下单, 简单轻松,节省科学家宝贵的科研时间。为您竭诚服务!

【订购】蚂蚁淘生物科技  联系方式:4000-520-616

更多产品,更多优惠!请联系我们!

苏州蚂蚁淘生物科技有限公司

免费热线:4000-520-616

官网:https://www.ebiomall.cn/



affinity biologicals等离子产品不足

Affinity Biologics是血浆不足产品的领先制造商。我们的血浆不足产品是由经过筛选的正常柠檬酸人类血浆制备而成的,这些血浆已通过FDA批准的方法进行了测试,并发现对HIV和肝炎呈阴性。我们的制造过程使我们能够通过选择性亲和免疫吸附来耗尽特定靶蛋白的血浆,而使其他凝血蛋白保持完整。


自营商城图标
厂家直采
全球直采模式 正品优价
正品保障图标
正品保障
厂家直发 有线跟踪
解放采购图标
正规清关
CIF100%正规报关,提供发票
及时交付图标
及时交付
限时必达 不达必赔
在线客服
客服电话

4000-520-616

0512-67156496